Silicon in PDB 1fuq: Fumarase with Bound 3-Trimethylsilylsuccinic Acid

All present enzymatic activity of Fumarase with Bound 3-Trimethylsilylsuccinic Acid:
4.2.1.2;

The structure of Fumarase with Bound 3-Trimethylsilylsuccinic Acid, PDB code: 1fuq was solved by T.Weaver, L.Banaszak, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	104.000, 219.900, 86.700, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 23.3

The binding sites of Silicon atom in the Fumarase with Bound 3-Trimethylsilylsuccinic Acid (pdb code 1fuq). This binding sites where shown within 5.0 Angstroms radius around Silicon atom.
In total 2 binding sites of Silicon where determined in the Fumarase with Bound 3-Trimethylsilylsuccinic Acid, PDB code: 1fuq:
Jump to Silicon binding site number: 1; 2;

Silicon binding site 1 out of 2 in the Fumarase with Bound 3-Trimethylsilylsuccinic Acid


Mono view


Stereo pair view

A full contact list of Silicon with other atoms in the Si binding site number 1 of Fumarase with Bound 3-Trimethylsilylsuccinic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Si1000 b:51.6 occ:1.00 SI A:SIF1000 0.0 51.6 1.0 C7 A:SIF1000 1.5 45.3 1.0 C5 A:SIF1000 1.5 47.6 1.0 C3 A:SIF1000 1.5 39.7 1.0 C6 A:SIF1000 1.5 43.0 1.0 C2 A:SIF1000 2.4 46.5 1.0 C4 A:SIF1000 2.5 42.7 1.0 O3 A:SIF1000 3.3 43.0 1.0 O4 A:SIF1000 3.3 39.9 1.0 C1 A:SIF1000 3.8 45.9 1.0 ND1 A:HIS129 4.0 39.1 1.0 O1 A:SIF1000 4.2 35.9 1.0 CE1 A:HIS129 4.3 38.3 1.0 O2 A:SIF1000 4.8 38.1 1.0 CG A:HIS129 4.9 38.5 1.0

Silicon binding site 2 out of 2 in the Fumarase with Bound 3-Trimethylsilylsuccinic Acid


Mono view


Stereo pair view

A full contact list of Silicon with other atoms in the Si binding site number 2 of Fumarase with Bound 3-Trimethylsilylsuccinic Acid within 5.0Å range: probe atom residue distance (Å) B Occ B:Si1001 b:44.1 occ:1.00 SI B:SIF1001 0.0 44.1 1.0 C5 B:SIF1001 1.5 38.5 1.0 C7 B:SIF1001 1.5 42.8 1.0 C3 B:SIF1001 1.5 34.2 1.0 C6 B:SIF1001 1.5 32.9 1.0 C2 B:SIF1001 2.4 39.5 1.0 C4 B:SIF1001 2.5 35.6 1.0 O3 B:SIF1001 3.3 30.5 1.0 O4 B:SIF1001 3.3 28.3 1.0 C1 B:SIF1001 3.8 37.9 1.0 ND1 B:HIS129 4.0 35.3 1.0 O1 B:SIF1001 4.2 35.4 1.0 CE1 B:HIS129 4.4 36.6 1.0 CE B:MET124 4.5 35.7 1.0 O2 B:SIF1001 4.8 37.3 1.0

T.Weaver, L.Banaszak. Crystallographic Studies of the Catalytic and A Second Site in Fumarase C From Escherichia Coli. Biochemistry V. 35 13955 1996.
ISSN: ISSN 0006-2960
PubMed: 8909293
DOI: 10.1021/BI9614702